2013 Fiscal Year Final Research Report
Application of new generation PET to brain tumor treatment strategy
| Project/Area Number |
23591744
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Hokkaido University |
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Principal Investigator |
SHIGA Tohru 北海道大学, 医学(系)研究科(研究院), 准教授 (80374495)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 機能イメージング / 脳腫瘍 / 治療戦略 |
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| Research Abstract |
The purpose of this study was to reveal the usefulness of molecular imaging in strategy of brain tumor treatment. We used two technique for the purpose. One was to investigate relationships between molecular imaging and brain tumor pathology, another was to investigate the superiority of high spatial resolution and high energy resolution PET system in molecular imaging. We clarified that hypoxia imaging differentiated glioblastoma from other grade glioma and high spatial and energy resolution PET could produce high regression between FDG uptake and tumor proliferation.
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[Journal Article] F-18 -Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas2012
Author(s)
Hirata K, Terasaka S, Shiga T, Hattori N, Magota K, Kobayashi H, Yamaguchi S, Houkin K, Tanaka S, Kuge Y, Tamaki N
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Journal Title
Eur J Nucl Med Mol Imaging
Volume: 39(5)
Pages: 760-70
Peer Reviewed
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