2013 Fiscal Year Final Research Report
Evaluation of abdominal organ and tumor with IVIM-MR imaging
| Project/Area Number |
23591758
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Gifu University |
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Principal Investigator |
WATANABE Haruo 岐阜大学, 医学(系)研究科(研究院), 非常勤講師 (30456529)
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| Co-Investigator(Kenkyū-buntansha) |
KANEMATSU Masayuki 岐阜大学, 医学部附属病院, 准教授 (40252134)
GOSHIMA Satoshi 岐阜大学, 医学部附属病院, 助教 (90402205)
KONDO Hiroshi 岐阜大学, 医学部附属病院, 講師 (20324311)
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| Project Period (FY) |
2011 – 2013
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| Keywords | IVIM |
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| Research Abstract |
One hundred and twenty hepatic lesions (34 metastases, 32 hepatocellular carcinoma [HCC], 33 hemangiomas, and 21 liver cysts) in 74 patients were examined. Mean D, D*, f, and ADC values of hepatic lesions were compared among pathologies. ROC curve analyses were performed to assess the performances of D, D*, f, and ADC values for the characterization of liver lesions as benign or malignant. The mean D and ADC values of benign lesions were greater than those of malignant lesions (P<.001). Sensitivity and specificity for the detection of malignant lesion were 89% and 98%, respectively, when an ADC cut-off value of 1.40 was applied. D and ADC values have more potential for characterizing focal hepatic lesions than D* or f values, and for the differentiation of malignancy and benignity.
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