2013 Fiscal Year Final Research Report
Prediction of post-operative pulmonary function for lung cancer patients with COPD using computer-aided diagnosis.
| Project/Area Number |
23591815
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nagoya University |
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Principal Investigator |
IWANO Shingo 名古屋大学, 医学(系)研究科(研究院), 准教授 (90335034)
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| Co-Investigator(Kenkyū-buntansha) |
NAGANAWA Shinji 名古屋大学, 医学系研究科, 教授 (50242863)
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| Co-Investigator(Renkei-kenkyūsha) |
USAMI Niriyasu 名古屋大学, 医学部附属病院, 助教 (30378179)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 呼吸機能検査 / 3次元CT / COPD / 肺癌 |
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| Research Abstract |
In this study, we developed novel computer-aided diagnosis (CAD) to measure the total volume and the emphysematous volume of each anatomic lobe from three-dimensional CT (3D-CT) images. This CAD could semi-automatically or automatically recognize inter-lobar fissures. We acquired 50 consecutive preoperative 3D-CT examinations for lung tumours. We calculated the lobar volume and the emphysematous lobar volume <-950 HU of each lobe using (i) the slice-by-slice method (reference standard), (ii) number of segments method, and (iii) semi-automatic and (iv) automatic computeraided diagnosis. As a result, the lobar volumetry CAD system could measure each lobar volume more precisely than the conventional number of segments method. This results show that lobar volumetry CAD may more precisely predict postoperative pulmonary function than the number of segments method.
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