2013 Fiscal Year Final Research Report
Prediction of PSA bounce after I-125 prostate brachytherapy
| Project/Area Number |
23591848
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Tokai University (2012-2013)
Keio University (2011) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | 前立腺癌 / 放射線治療 |
|---|
| Research Abstract |
The purpose of the present study was to determine factors that were associated with PSA bounce after I-125 prostate brachytherapy for patients with prostate cancer. After I-125 prostate brachytherapy, PSA was examined periodically. PSA bounce was defined as a rise of at least 0.1 ng/ml greater than a previous PSA level with a subsequent decline equal to, or less than, the initial nadir. As a result, PSA bounce occurred in 32% of patients. The incidence of PSA bounce was significantly higher in younger patients (<=67 years). In multivariate analysis, age was significantly associated with PSA bounce.
|
