2013 Fiscal Year Final Research Report
Estrogen receptor positive breast cancer risk score constructed by genetic factors and endogenous hormones
Project/Area Number |
23591901
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
General surgery
|
Research Institution | Nagoya City University |
Principal Investigator |
YOSHIMOTO Nobuyasu 名古屋市立大学, 医学(系)研究科(研究院), 助教 (10551244)
|
Co-Investigator(Kenkyū-buntansha) |
YAMASHITA Hiroko 名古屋市立大学, 大学院医学研究科, 准教授 (70332947)
TOYAMA Tastuya 名古屋市立大学, 大学院医学研究科, 准教授 (30315882)
|
Project Period (FY) |
2011 – 2013
|
Keywords | エストロゲンレセプター陽性乳癌 / リスクモデル |
Research Abstract |
To identify estrogen receptor breast cancer high risk group, we analyzed datas both estrogen receptor positive breast cancer patients and control women. We analyzed epidemiological factors, single nucleotide polymorphism and serum biomarker both ER positive breast cancer patients and control women. We constructed ER positive breast cancer risk model among both premenopausal women and postmenopausal women by logistic regression analysis.
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[Journal Article] Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women2011
Author(s)
Yoshimoto N, Nishiyama T, Toyama T, Takahashi S, Shiraki N, Sugiura H, Endo Y, Iwasa M, Fujii Y, Yamashita H
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Journal Title
Cancer Science
Volume: 102
Pages: 2065-72
DOI
Peer Reviewed
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[Presentation] Genetic polymorphism of estrogen metabolizing enzyme CYP17A1 rs743572 impacts on serum testosterone level in Japanese premenopausal women2013
Author(s)
Yoshimoto N, Nishiyama T, Yamashita H, Takahashi S, Shiraki N, Sugiura H, Endo Y, Iwasa M, Asano T, Hato Y, Fujii Y, Toyama T
Organizer
36th Annual Breast Cancer Symposium
Place of Presentation
San Antonio
Year and Date
2013-12-13
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[Presentation] A mammographic density prediction model using environment factors, endogenous hormones and growth factors in Japanese women2012
Author(s)
Yoshimoto N, Nishiyama T, Toyama T, Takahashi S, Shiraki N, Sugiura H, Endo Y, Iwasa M, Asano T, Fujii Y, Yamashita H
Organizer
35th Annual San Antonio Breast Cancer Symposium
Place of Presentation
San Antonio
Year and Date
2012-12-06
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[Presentation] Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women2011
Author(s)
Yoshimoto N, Nishiyama T, Toyama T, Takahashi S, Shiraki N, Sugiura H, Endo Y, Iwasa M, Fujii Y, Yamashita H
Organizer
34th Annual San Antonio Breast Cancer Symposium
Place of Presentation
San Antonio
Year and Date
2011-12-09
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