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2013 Fiscal Year Final Research Report

Peptide-cocktail vaccination for hepatocellular carcinoma

Research Project

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Project/Area Number 23592000
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionKinki University

Principal Investigator

ISHIKAWA Hajime  近畿大学, 医学部, 講師 (90309302)

Co-Investigator(Kenkyū-buntansha) OKUNO Kiyotaka  近畿大学, 医学部, 教授 (30169239)
TAKEYAMA Yoshifumi  近畿大学, 医学部, 教授 (70263374)
NAKAI Takuya  近畿大学, 医学部, 准教授 (60227725)
Project Period (FY) 2011 – 2013
Keywords肝癌ワクチン治療 / 免疫治療
Research Abstract

We performed the peptide-cocktail vaccination for hepatocellular carcinoma. The vaccine mixes an adjuvant with WDRPUH, FOXM1, MELK, HJURP-derived and HLA-A24-restricted epitope peptides. The vaccine was tried on five liver cancer patients till the present. One patient had reduction of the tumor. The other patient had SD. Although adverse events were skin induration and gastrointestinal bleeding, both were two or less grades.

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    • URL

      https://www.facebook.com/pages/%E8%82%9D%E7%99%8C%E3%83%AF%E3%82%AF%E3%83%81%E3%83%B3/135021826686415

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Published: 2015-07-16  

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