2013 Fiscal Year Final Research Report
The effect of prophylactic preoperative endoscopic transpapillary pancreatic stenting on clinically significant pancreatic fistula following distal pancreatectomy
| Project/Area Number |
23592008
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Kobe University |
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Principal Investigator |
MATSUMOTO Ippei 神戸大学, 医学部附属病院, 病院准教授 (30379408)
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| Co-Investigator(Kenkyū-buntansha) |
SHINZEKI Makoto 神戸大学, 医学部附属病院, 病院講師 (60444593)
TOYAMA Hirochika 神戸大学, 医学(系)研究科(研究院), 医学研究員 (10444598)
ASARI Sadaki 神戸大学, 医学部附属病院, 特定助教 (20580682)
GOTO Tadahiro 神戸大学, 医学部附属病院, 特定助教 (40580684)
HORI Yuichi 神戸大学, 保健学研究科, 教授 (80248004)
KU Yonson 神戸大学, 医学(系)研究科(研究院), 教授 (40195615)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 膵管ステント / 尾側膵切除術 / 術後膵液瘻 / 膵体尾部切除術 |
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| Research Abstract |
Postoperative pancreatic fistula (PF) causes major morbidity after distal pancreatectomy (DP). The purpose of this prospective study is to determine whether prophylactic preoperative endoscopic transpapillary pancreatic stenting (EPS) reduces PF formation after DP. Fifteen patients underwent DP following EPS. Clinically significant PF (ISGPF [the International Study Group on Pancreatic Fistula] classification Grade B and C) occurred in 4 (26.7%). We decided to terminate the study after internal analysis because our study design required 35 patients with estimated PF rate 10%.
Prophylactic preoperative EPS dose not reduce PF after DP.
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