• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2013 Fiscal Year Final Research Report

Establishment of a new perioperative glycemic control for diabetes patients using progressive artificial pancreas

Research Project

  • PDF
Project/Area Number 23592011
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionKochi University

Principal Investigator

HANAZAKI KAZUHIRO  高知大学, 教育研究部医療学系, 教授 (30240790)

Co-Investigator(Kenkyū-buntansha) KITAGAWA Hiroyuki  高知大学, 教育研究部医療学系, 助教 (10403883)
YATABE Tomoaki  高知大学, 教育研究部医療学系, 助教 (60437720)
UEHARA Yoshio  新潟大学, 医歯(薬)学総合研究科, その他 (60346723)
Project Period (FY) 2011 – 2013
Keywords人工膵臓 / 糖尿病 / 周術期 / 血糖管理
Research Abstract

Since final enrolment of surgical patients with diabetes mellitus (DM) has not been established yet, this study is going on under enrolment in targeting number of 150 patients, and further enrolment of patients is mandatory to complete this study. However, we conducted retrospective large study to examine usability, blood glucose measurements, and glycemic control characteristics of novel artificial pancreas (AP) (STG-55) and conventional AP (STG-22). As a result, perioperative intensive insulin therapy (IIT) using an AP in 305 patients with or without DM can be used to prevent hypoglycemia and maintain stable glycemic control with less variability of blood glucose concentration. The usability, performance with respect to blood glucose measurement, and glycemic control characteristics of IIT were comparable between novel and conventional AP systems.Also STG-55 was easier to manipulate than STG-22 due to its smaller size, lower weight, and shorter time for preparation.

  • Research Products

    (19 results)

All 2013 2012 2011

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (5 results) Book (4 results)

  • [Journal Article] Perioperative glycemic control using an artificial endocrin epancreas in patients undergoing total pancreatectomy : Tight glycemic control may be justified in order to avoid brittle diabetes2013

    • Author(s)
      Hanazaki K, Yatabe T, Kobayashi M, T sukamoto Y, Kinoshita Y, Munekage M, Kitagawa H.
    • Journal Title

      Bio-Medical Materials and Engineering

      Volume: 23 Pages: 109-116

    • DOI

      10.3233/BME-120736

    • Peer Reviewed
  • [Journal Article] Evaluation of a Novel Artificial Pancreas : Closed Loop Glycemic Control System with Continuous Blood Glucose Monitoring2013

    • Author(s)
      Tsukamoto Y, Kinoshita Y, Kitagawa H, Munekage M, Munekage E, Takezaki Y, Yatabe T, Yamashita K, Yamazaki R, Okabayashi T, Tarumi M, Kobayashi M, Mishina S, Hanazaki K.
    • Journal Title

      Artif Organs

      Volume: 37 Pages: E67-73

    • DOI

      10.1111/aor.12068

    • Peer Reviewed
  • [Journal Article] Preoperative oral rehydrati on therapy with 2.5% carbohydrate be verage alleviates insulin action in volunteers2013

    • Author(s)
      Yatabe T, Tamura T, Kitagawa H, Namikawa T, Yamashita K, Hanazaki K, Yokoyama M.
    • Journal Title

      J Artif Organs

      Volume: 16 Pages: 483-488

    • DOI

      10.1007/s100047-013-0722-4

    • Peer Reviewed
  • [Journal Article] Development of perioperative glycemic control us ing an artificial endocrine pancreas2013

    • Author(s)
      Hanazaki K, Namikawa T.
    • Journal Title

      Conf Proc IEEE Eng Med boil Soc.

      Pages: 5719-5722

    • DOI

      10.1109/EMBC2013.6610849

    • Peer Reviewed
  • [Journal Article] Tight glycemic control using an artificial endocrine pancreas may play an important role in preventing infection after pancreatic resection2012

    • Author(s)
      Hanazaki K.
    • Journal Title

      World J Gastroenterol

      Volume: 18(29) Pages: 3787-3789

    • DOI

      10.3748/wjg.v18.i29.3787

    • Peer Reviewed
  • [Journal Article] Blood glucose control using an artificial pancreas reduces the workload of ICU nurses2012

    • Author(s)
      Mibu K, Yatabe T, Hanazaki K.
    • Journal Title

      J Artif Organs

      Volume: 15 Pages: 71-76

    • DOI

      10.1007/s10047-011-0611-7

    • Peer Reviewed
  • [Journal Article] Progressive artificial endocrine pancreas : The era of novel periopera tive blood glucose control for surgery2011

    • Author(s)
      Tsukamoto Y, Okabayashi T, Hanazaki K.
    • Journal Title

      Surg Today

      Volume: 41 Pages: 1344-1351

    • DOI

      10.1007/s00595-011-4537-8

    • Peer Reviewed
  • [Journal Article] What is the optimal blood glucose range to improve morbidity and mortality in surgical patients?2011

    • Author(s)
      Hanazaki K, Munekage M, Okabayashi T.
    • Journal Title

      Ann Surg

      Volume: 254 Pages: 671-672

    • DOI

      10.1097/SLA.0b013e3182306816

    • Peer Reviewed
  • [Journal Article] What should the targeted range of blood glucose levels be to reduce the incidence of surgical site infection following general surgery?2011

    • Author(s)
      Hanazaki K, Okabayashi T.
    • Journal Title

      Arch Surg

      Volume: 146 Pages: 368-369

    • DOI

      10.1001/archsurg.2011.16

    • Peer Reviewed
  • [Journal Article] Determination of the optimal periop erative blood glucose level to reduce surgical site infection in diabetic patients2011

    • Author(s)
      Hanazaki K, Kitagawa H, Okabayashi T.
    • Journal Title

      J Am Coll Surg

      Volume: 213(1) Pages: 198-199

    • DOI

      10.1016/j.jamcollsurg.2011.04.021

    • Peer Reviewed
  • [Presentation] Developm ent of perioperative glycemic control using an artificial endocrine pancreas2013

    • Author(s)
      Hanazaki K, Namikawa T.
    • Organizer
      35^<th> Annual International Conference IEEE EMBS
    • Place of Presentation
      大阪国際会議場,Osaka, Japan
    • Year and Date
      20130703-07
  • [Presentation] Intensive insulin therapy using an artificial pancre as with closed-loop system(Symposium)2013

    • Author(s)
      Hanazaki K.
    • Organizer
      13^<th> Annual Rachmiel Levine Diabetes and Obesity Symposium
    • Place of Presentation
      The Langham Huntington Hotel, Pasadena, USA
    • Year and Date
      20130313-16
  • [Presentation] Perioperative intensive insulin therapy using an artific ial endocrine pancreas with clos ed-loop glycemic control system : the impact of no hypoglycemia2013

    • Author(s)
      Hanazaki K, Kiatgawa H, Yatabe T, Munekage M, Ichikawa K, Takezak i Y, Tsukamoto Y, Asano T, Kinoshita Y.
    • Organizer
      6^<th> International Conference Advanced Technologies Treatment Diabetes (ATTD 2013)
    • Place of Presentation
      CNIT Paris La Defense,Paris, France
    • Year and Date
      20130227-0302
  • [Presentation] Perioperative glycemic control using an artificial endocrine pancreas in patients undergoing total pancreatectomy2013

    • Author(s)
      Hanazaki K, Munekage M, Kitagwa H, Tsukamoto Y, Yatabe T, Namikawa T.
    • Organizer
      13^<th> Annual Diabetes Technology Meeting
    • Place of Presentation
      Hyatt Regency San Francisco Airport, San Franci sco, USA
    • Year and Date
      2013-10-31
  • [Presentation] ERASを目指した人工膵臓を用いた外科周術期血糖管理2012

    • Author(s)
      花﨑和弘
    • Organizer
      第112回日本外科学会摘学術集会
    • Place of Presentation
      幕張メッセ、ホテルニューオータニ幕張、ランチョンセミナー、千葉
    • Year and Date
      20120412-14
  • [Book] 臨床に役立つ最新血糖管理マニュアル、II章外科領域:外科周術期の血糖管理の意義2012

    • Author(s)
      花﨑和弘、小川道雄
    • Total Pages
      89-95
    • Publisher
      医学図書出版
  • [Book] 臨床に役立つ最新血糖管理マニュアル、II章外科領域:人工膵臓を用いた外科周術期血糖管理2012

    • Author(s)
      花﨑和弘、小川道雄
    • Total Pages
      163-169
    • Publisher
      医学図書出版
  • [Book] 臨床に役立つ最新血糖管理マニュアル、II章外科領域:膵臓外科周術期の血糖管理2012

    • Author(s)
      宗景匡哉、花﨑和弘
    • Total Pages
      114-120
    • Publisher
      医学図書出版
  • [Book] 臨床に役立つ最新血糖管理マニュアル、II章外科領域:食道外科周術期の血糖管理2012

    • Author(s)
      北川博之、花﨑和弘
    • Total Pages
      121-125
    • Publisher
      医学図書出版

URL: 

Published: 2015-07-16  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi