2013 Fiscal Year Final Research Report
Transportation for spinal cord regeneration inducing angiogenesis
| Project/Area Number |
23592124
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka University |
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Principal Investigator |
IWATSUKI Koichi 大阪大学, 医学(系)研究科(研究院), 講師 (80346204)
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| Co-Investigator(Kenkyū-buntansha) |
TOSHIKI Yoshimine 大阪大学, 大学院医学系研究科, 教授 (00201046)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 脊髄・脊椎疾患学 |
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| Research Abstract |
olfactory mucosa transplantation following spinal cord injury can support at least partial hind limb motor recovery. In this study, we identified numerous axons surrounding the transplanted cells, and penetrating the mucosa at the transplant site without marginal spinal white matter. Olfactory mucosa might therefore be a more suitable scaffold for axonal regeneration than white matter, which contains inhibiting factors for axonal regeneration in the spinal cord.
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