Development of a fiber-optic intravenous catheter system for continuous blood glucose concentration monitoring

2014 Fiscal Year Final Research Report

• Project/Area Number: 23592282
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: DOI MATSUYUKI 浜松医科大学, 医学部附属病院, 准教授 (10155616)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 光技術 / 血中濃度測定 / ブドウ糖

Outline of Final Research Achievements

The aim of this study was to develop a fiber-optic intravenous catheter system for continuous blood glucose concentration monitoring. We investigated materials as blood glucose sensor to be mounted on the tip of the catheter. We found anthracene-phenyl-diboronic acid was suitable as the sensor. It emitted 430 nm fluorescence with 370 nm excitation light. The intensity of the fluorescence depended on glucose concentration up to 400 mg/dl, but gradually diminished beyond 12 hours monitoring time. Anthracene-phenyl-diboronic acid was one of promising glucose sensors, but required improvement of long time sutability.

Free Research Field

集中治療医学