2013 Fiscal Year Final Research Report
A trial of the establishment of the umbilical cord blood stem cell transplantation for the neonatal brain injury: a search for the effective transplantation -
| Project/Area Number |
23592402
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Osaka University |
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Principal Investigator |
KANAGAWA Takeshi 大阪大学, 医学(系)研究科(研究院), 助教 (40346218)
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| Co-Investigator(Kenkyū-buntansha) |
TANIGUCHI Yukiko 大阪大学, 医学系研究科, 助教 (60423175)
MIMURA Kazuya 大阪大学, 医学系研究科, 助教 (50437422)
TOMIMATSU Takuji 川崎医科大学, 医学部, 准教授 (30346209)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 新生児低酸素虚血性脳障害 / 胎児付属物 / 幹細胞 / カフェイン / NF-κB / プレコンディショニング |
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| Research Abstract |
The Perinatal brain damage due to the fetal distress or neonatal distress remains the most important problem although the perinatal care develops rapidly remarkably.
The aims of this research are the decrease the perinatal damage.In this research,we discovered that the short-term treatment of caffeine induced the neuroprotection which is attributed from the activation of NF-kappaB.
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[Journal Article] Hypoxic preconditioning increases triiodothyronine (T3) level in the developing rat brain2013
Author(s)
Minato K, Tomimatsu T, Mimura K, Jugder O, Kakigano A, Kanayama T, Fujita S, Taniguchi Y, Kanagawa T, Endo M, Kimura T
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Journal Title
Brain Res
Volume: 1501
Pages: 89-97
Peer Reviewed
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[Journal Article]
Author(s)
Tomimatsu T, Kakigano A, Mimura K, Kanayama T, Koyama S, Fujita S, Taniguchi Y, Kanagawa T, Kimura T
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