2013 Fiscal Year Final Research Report
Risk factors for eye diseases in the Hisayama study
| Project/Area Number |
23592575
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Kyushu University |
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Principal Investigator |
YASUDA Miho (宮崎 美穂) 九州大学, 大学病院, 助教 (00336033)
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| Co-Investigator(Kenkyū-buntansha) |
ISHIBASHI Tatsuro 九州大学, 大学院医学研究院眼科学分野, 教授 (30150428)
KIYOHARA Yutaka 九州大学, 大学院医学研究院環境医学分野, 教授 (80161602)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 疫学研究 / 危険因子 / 予防因子 / 有病率 / 発症率 / 加齢黄斑変性 / 糖尿病網膜症 / 近視性網膜症 |
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| Research Abstract |
Glaucoma, diabetic retinopathy, and age-related macular degeneration (AMD) are the leading causes of irreversible visual impairment and blindness in elderly populations in Japan. Despite the magnitude of this problem, the pathogenesis of these diseases remains poorly understood. It is thus very important to determine the precise epidemiology of these diseases and to identify their risk factors to develop preventive measures of the disease. The purpose of this study was to examine the incidence of eye diseases and their risk factors in a prospective study of a general Japanese population.
Our findings suggest that the 9-year incidences of late AMD are lower among the Japanese than among white people in Western countries, while it is higher than among black people. Smoking habits and higher circulating WBC count are significant risk factors for the development of late AMD in the Japanese.
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