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2013 Fiscal Year Final Research Report

Development of prevention adhesion sheet composed of hyaluronic acid and collagen sponge containing epidermal growth factor

Research Project

  • PDF
Project/Area Number 23592653
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Plastic surgery
Research InstitutionKitasato University

Principal Investigator

NEMOTO Mitsuru  北里大学, 医学部, 講師 (20276083)

Co-Investigator(Kenkyū-buntansha) KUROYANAGI Yoshimitsu  北里大学, 医療衛生学部, 教授 (80170140)
KUMAZAWA Kenichi  北里大学, 医学部, 助教 (60383618)
Project Period (FY) 2011 – 2013
Keywords癒着防止膜 / ヒアルロン酸 / コラーゲン / 腱損傷 / 手外科
Research Abstract

The aim of this study has revealed effects of prevention adhesion sheet composed of hyaluronic acid and collagen sponge in chicken model. We presented effects of prevention adhesion sheet applied for tendon sheath injury in the 56th annual meeting of the Japanese society for surgery of the hand at Yokohama, and applied for tendon injury in the 57th annual meeting of the Japanese society for surgery of the hand at Kobe. However, prevention adhesion sheet applied tendon injury model of chicken occurred limitation of range of motion. Then, we have improved prevention adhesion sheet composed of hyaluronic acid and collagen sponge for postoperative early exercise. We will present these results of prevention adhesion sheet in 10th congress of Asian pacific federation of societies for surgery of the hand at Malaysia.

  • Research Products

    (10 results)

All 2014 2013 2012 2011

All Journal Article (8 results) (of which Peer Reviewed: 5 results) Presentation (2 results)

  • [Journal Article] Development on novel wound dressing composed of hyaluronic acid and collagen sponge containing epidermal growth factor and vitamin C derivative2014

    • Author(s)
      Niiyama H, Kuroyanagi Y
    • Journal Title

      J Artif Organs

      Volume: 17 Pages: 81-87

    • DOI

      10.1007/s10047-013-0727-x

    • Peer Reviewed
  • [Journal Article] Potential of wound dressing composed of hyaluronic acid containing epidermal growth factor to enhance cytokine production by fibroblasts2013

    • Author(s)
      Yamamoto A, Shimizu N, Kuriyanagi Y
    • Journal Title

      J Artif Organs

      Volume: 16 Pages: 489-194

    • DOI

      10.1007/s10047-013-0726-0

    • Peer Reviewed
  • [Journal Article] Development of an artificial dermis composed of hyaluronic acid and collagen2013

    • Author(s)
      Mineo A,Kuroyanagi Y
    • Journal Title

      J Biomater Sci Ploym Ed

      Volume: 24 Pages: 726-740

    • DOI

      10.1080/09205063.2012708190

    • Peer Reviewed
  • [Journal Article] Safety and utility of a PMMA-based tissue adhesive for closure of surgical incision wounds2013

    • Author(s)
      Suzuki R, Kuroyanagi Y
    • Journal Title

      J Biomater Sci Polym Ed

      Volume: 24 Pages: 287-300

    • DOI

      10.1080/09205063.2012.708190

    • Peer Reviewed
  • [Journal Article] Potential of a cryopreserved cultured dermal substitute composed of hyaluronic acid and collagen to release angiogenic cytokine2013

    • Author(s)
      Sawa M,Kuroyanagi Y
    • Journal Title

      J Biomater Sci Polym Ed

      Volume: 24 Pages: 224-238

    • DOI

      10.1163/156856212X631888

    • Peer Reviewed
  • [Journal Article] アドバンスト・ウンド・マネジメントTHEテクニック生体材料・細胞成長因子・細胞を応用した新しい創傷治療2012

    • Author(s)
      黒柳能光
    • Journal Title

      日本創傷・オストミー・失禁管理学会誌

      Volume: 15 Pages: 270-270

  • [Journal Article] 再生医療のいま基礎研究から臨床への展開に向けて細胞・細胞成長因子・生体材料を応用した皮膚再生医療2011

    • Author(s)
      黒柳能光
    • Journal Title

      治療

      Volume: 93 Pages: 1946-1952

  • [Journal Article] 細胞・細胞成長因子・生体材料を応用した皮膚再生医療2011

    • Author(s)
      黒柳能光
    • Journal Title

      日本創傷・オストミー・失禁管理学会誌

      Volume: 15 Pages: 16-24

  • [Presentation] ヒアルロン酸とコラーゲンを組み合わせた癒着防止膜の開発第2報−機能的評価—2013

    • Author(s)
      根本充、熊澤憲一、内沼栄樹
    • Organizer
      第56回日本手外科学会学術集会
    • Place of Presentation
      神戸市
    • Year and Date
      2013-04-19
  • [Presentation] ヒアルロン酸とコラーゲンを組み合わせた新規癒着防止膜の開発第1報−組織学的評価−2012

    • Author(s)
      根本充、熊澤憲一、内沼栄樹
    • Organizer
      第55回日本手外科学会学術集会
    • Place of Presentation
      横浜市
    • Year and Date
      2012-04-19

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Published: 2015-07-16  

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