2013 Fiscal Year Final Research Report
Change of brain blood flow with BOLD MRI during expired gas contorol
| Project/Area Number |
23592677
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Emergency medicine
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| Research Institution | Nagoya City University |
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Principal Investigator |
ITO Shoji 名古屋市立大学, 医学(系)研究科(研究院), 研究員 (40254289)
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| Co-Investigator(Kenkyū-buntansha) |
SASANO Hiroshi 名古屋市立大学, 大学院医学研究科, 准教授 (20215742)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 呼気ガスコントロール / 二酸化炭素 / 酸素 / 脳血流 / BOLD MRI |
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| Research Abstract |
The simulator for elimination of carbon dioxide (CO2) and adsorption of oxygen (O2) was created, based on our CO2 & O2 transport model in the body. The auto end-tidal carbon dioxide & oxygen pressure (PETCO2&O2) independent control system installing the simulator was developed. The system was applied to subjects with spontaneous breathing and the PETCO2&O2 control tests were performed. In consequence the precise and independent PETCO2&O2 control method was established. We are investigating the relationships between PETCO2&O2 data and brain blood flow from BOLD fMRI image during PETCO2&O2 up & down step change in spontaneous breathing subjects.
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