2013 Fiscal Year Final Research Report
Establishment of the assessment method of salivery function by perfusion/diffusion MR imaging without using contrast agent.
| Project/Area Number |
23592772
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nagasaki University |
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Principal Investigator |
SASAKI Miho 長崎大学, 大学病院, 助教 (10437874)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Takashi 長崎大学, 医歯(薬)学総合研究科, 教授 (30172406)
SUMI Misa 長崎大学, 医歯(薬)学総合研究科, 准教授 (90284702)
KIMURA Yasuo 長崎大学, 医歯(薬)学総合研究科, 助教 (30253686)
EIDA Sato 長崎大学, 医歯(薬)学総合研究科, 助教 (80325662)
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| Project Period (FY) |
2011 – 2013
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| Keywords | MRI / 灌流 / 拡散 / 唾液腺機能 |
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| Research Abstract |
The aim of this study is to establish the new evaluation technique for the assessment of salivary gland perfusion and diffusion function using diffusion weighted MR imaging. Various diffusion weighted MR imaging parameters were tested, such as b-values, TRs and TEs, number of acquisition. We could achieve the imaging time within 10sec, which was enough to evaluating the salivary function before and after gustatory stimulation. We also established the head fixing gear and gustatory stimulation appliance. Healthy volunteer study revealed the good performance of this newly established method.
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