2013 Fiscal Year Final Research Report
Diagnosis of TMJ pain by visualization of protein concentration in TMJ fluid
| Project/Area Number |
23592777
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Showa University (2013)
Tokyo Dental College (2011-2012) |
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Principal Investigator |
SANO Tsukasa 昭和大学, 歯学部, 教授 (40241038)
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI Tetsu 東北大学, 歯学部, 教授 (60226850)
WAKOH Mamoru 東京歯科大学, 歯学部, 准教授 (70211670)
OTONARI Mika 東京歯科大学, 歯学部, 講師 (30276604)
SAKAMOTO Junichiro 東京歯科大学, 医歯(薬)学総合研究科, 助教 (40506896)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 顎関節 / MRI / 関節液 / 疼痛 / 蛋白濃度 |
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| Research Abstract |
The purpose is to visualize the difference in protein concentration of joint effusion of the temporomandibular joint (TMJ) by FLAIR technique which is inversion recovery method of MRI and to clarify the relationship between the pain and the protein concentration. A diagnosis of pain by the signal intensity ratio (SIR) was indicated in TMJ with disc displacement without reduction. Furthermore, as a result of a study by setting the pain value and SIR, sensitivity: 0.75, specificity: 1.0, positive predictive value: 1.0, negative predictive value: 0.5, accuracy of 0.8 was obtained. It was suggested that by the SIR obtained from the JE, pain in the TMJ can be diagnosed.
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