2013 Fiscal Year Final Research Report
The study of the gene distribution and the role in hard tissue formation of amelogenin
| Project/Area Number |
23592807
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Showa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MASUDA Yoshiko 昭和大学, 歯学部, 准教 (10297038)
KAWANAKA Takao 昭和大学, 歯学部, 助教 (10365702)
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| Project Period (FY) |
2011 – 2013
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| Keywords | アメロジェニン / マウス胎仔 / エクソン / In situ hybridization法 |
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| Research Abstract |
According to the results of in situ hybridization, amelogenin gene expression was observed several non tooth related tissue such as brain, kidney, eye and bone related tissues.
The amelogenin gene expression in these tissues, were a significant small amount of gene expression compared with gene expression in ameloblast of incisor. The tendency of the expression level of the amelogenin gene in the tissue they become strong in the late gestation than early fetal period has been confirmed.
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