Application of effect of low-magnitude and high-frequency loading on peri-implant bone to the implant

2013 Fiscal Year Final Research Report

• Project/Area Number: 23592835
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Tohoku University
• Principal Investigator: OGAWA Toru 東北大学, 大学病院, 講師 (50372321)
• Co-Investigator(Kenkyū-buntansha): SASAKI Keiichi 東北大学, 大学院歯学研究科, 教授 (30178644) ; IKEDA Kiyohiro 東北大学, 工学(系)研究科, 教授 (50168126) ; YAMAKAWA Yuki 東北大学, 工学(系)研究科, 准教授 (80324010) ; SHIGEMITSU Ryuji 東北大学, 大学病院, 助教 (00508921)
• Project Period (FY): 2011 – 2013
• Keywords: インプラント / 振動刺激 / 高周波 / オッセオインテグレーション / 有限要素 / メカノバイオロジー

Research Abstract

This study aimed to examine the influence of various loading on dynamic changes of bone-metabolism around the implant using a super-high resolution [18F]NaF-PET in rat tibiae. Adult male Wistar rats installed experimental implant on the tibia were used in this study. Increase of bone-metabolism was observed until 7 days after implantation surgery and then gradually decreased. Differences in bone-metabolism between immediate loading and no-loading group were found. This suggests loading affects bone-metabolism around the implant. Also

Research Products

• [Journal Article] Stimulation of titanium implant osseointegration through high frequency vibration loading is enhanced when applied at high acceleration (2014)
  • Author(s): Ogawa T, Vandamme K, Zhang X, Naert I, Possemiers T, Chaudhari A, Sasaki K, Duyck J.
  • Journal Title: Calcif Tissue Int Volume: (in press)
• [Journal Article] Influence of immediate and early loading on bone metabolic activity around dental implants in rat tibiae. ($ : Shared first authorship) (2013)
  • Author(s): Yamamoto M$, Ogawa T$, Yokoyama M, Koyama S, Sasaki K.
  • Journal Title: Clin Oral Implants Res Volume: (in press)
  • DOI: 10.1111/clr.12218
• [Journal Article] Stress distribution in the peri-implant bone with splinted and non-splinted implants by in vivo loading data-based finite element analysis (2013)
  • Author(s): Shigemitsu R, Ogawa T, Matsumoto T, Yoda N, Gunji Y, Yamakawa Y, Ikeda K, Sasaki K.
  • Journal Title: Odontology Volume: 101 Pages: 222-6
• [Presentation] [18F]NaF-PET Image Analyses of Peri-implant bone metabolism elicited Loading (2013)
  • Author(s): Matsuo Y, Yamamoto M, Ogawa T, Yokoyama M, Sasaki K.
  • Organizer: 7th East Asian Consortium on Biomedical Engineering
  • Place of Presentation: Taipei, Taiwan
  • Year and Date: 20131118-20
• [Presentation] Effect of low-magnitude and high-frequency loading on bone defect healing (2013)
  • Author(s): Kanda Y, Ogawa T, Vandamme K, Shibamoto A,Zhang X, Naert I, Sasaki K, Duyck J.
  • Organizer: 91th The International Association for Dental Research (IADR)
  • Place of Presentation: Seattle, USA
  • Year and Date: 20130320-23
• [Presentation] Evaluation of Peri-Implant Bone Metabolism with High-resolution-NaF-PET during Mechanical Loading (2012)
  • Author(s): Matsuo Y, Yamamoto M, Ogawa T, Yokoyama M, Sasaki K.
  • Organizer: The 60th Annual Meeting of Japanese Association for Dental Research
  • Place of Presentation: Niigata, Japan
  • Year and Date: 20121214-15