Development of diagnostic method of osteoporosis using the structural indices of mandibular alveolar bone.

2014 Fiscal Year Final Research Report

• Project/Area Number: 23592839
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Niigata University
• Principal Investigator: TANAKA MIKAKO 新潟大学, 医歯学総合病院, 講師 (20361909)
• Co-Investigator(Kenkyū-buntansha): EJIRI Sadakazu 朝日大学, 歯学部, 教授 (40160361) ; IDA Hiroko 新潟大学, 医歯学系, 准教授 (60293213) ; TANAKA Rei 新潟大学, 医歯学総合病院, 助教 (30323992) ; YAMADA Kazuho 新潟大学, 医歯学総合病院, 助教 (20397152) ; NOMURA Shuichi 新潟大学, 医歯学系, 教授 (40018859)
• Co-Investigator(Renkei-kenkyūsha): SAKURAI Naoki 新潟大学, 医歯学系, 助教 (50251830) ; YAMAMOTO Noriaki 新潟医療福祉大学, 骨の科学研究所, 転倒予防センター所長 (30445902) ; HAYASHI Takafumi 新潟大学, 医歯学系, 教授 (80198845)
• Research Collaborator: MIKAMI Emi
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 骨粗鬆症 / 下顎骨 / 微細骨梁構造 / 歯科用コーンビームCＴ / 骨形態計測 / 骨代謝マーカー / 踵骨骨密度

Outline of Final Research Achievements

The uni-lateral mandibles of ten elderly women were scanned using the dental cone beam CT device. The structural model index (SMI) and the star volume of mandibles showed significant relationships to the calcaneal bone density which was measured using Speed of Sound (SOS) with an ultrasound device. The node number (N.Nd) and the terminus number (N.Tm) as well as the bone surface (BS/TV) (%), trabecular number (Tb.N), and trabecular spacing (Tb. Spac) of mandibles significantly related to one of bone turnover markers, TRACP-5b. The present study therefore revealed changes in alveolar cancellous bone structure of elderly women, and also that this structure varies in relationship to the calcaneal bone density and some of bone turnover markers.

Free Research Field

歯科補綴学