2013 Fiscal Year Final Research Report
The study of ECM fixation for Ti implant with an artificial periodontal membrane
| Project/Area Number |
23592897
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Iwate Medical University |
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Principal Investigator |
SAITOH Setsuo 岩手医科大学, 歯学部, 講師 (70137537)
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| Project Period (FY) |
2011 – 2013
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| Keywords | チタンインプラント / 歯根膜 / 表面処理 / 金蒸着 / アルカンチオール |
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| Research Abstract |
A new method to enhance the biofunctionalization of Ti materials was developed by the immersion of Au-sputtered titanium plates into a solution of alkanethiol with a carboxy group end (HS-C11-COOH). X-ray photoelectron spectroscopy (XPS) analysis showed that the gold content increased with the Au sputtering time. The content of the characteristic alkanethiol elements (S, C, and O) in the immersed Ti specimens increased with the Au sputtering time, which indicates that the binding of alkanethiol molecules is enhanced by the Au modification on the Ti surface. Qualitative analysis of XPS (Au-S, COO-, and OH- species) and FTIR (peaks assignable to an aliphatic carboxylic acid) spectra for the sample after immersion also supported this. A strong positive correlation between the S and Au content confirms that Au sputtering is an effective method to control the alkanethiol treatment of Ti substrates.
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