2013 Fiscal Year Final Research Report
Detection of carcinoma cells in peripheral circulation by oncolgtic virus therapy
| Project/Area Number |
23592944
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Showa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KONDO Seiji 昭和大学, 歯学部, 准教授 (10432634)
MUKUDAI Yoshiki 昭和大学, 歯学部, 助教 (50325099)
KURIHARA Yuuji 昭和大学, 歯学部, 助教 (90514969)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 口腔癌 |
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| Research Abstract |
In this study, we investigated the detection of peripheral circulating tumor cells by an adenovirus included the GFP gene and the hTERT gene infected to oral carcinoma cells in circulating tumor cell model. Although we could confirm fluorescence in oral carcinoma cells, there were no relation between fluorescence and mRNA expression or protein expression. These results indicated that oral carcinoma cells would be circulate in peripheral blood flow in a certain period.
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