2013 Fiscal Year Final Research Report
The post-transcriptional regulatory system of gene expressionof in chondrocytes by ncleophosmin
| Project/Area Number |
23592998
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Showa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATORU Shintani 昭和大学, 歯学部, 教授 (80294429)
SEIJI Kondo 昭和大学, 歯学部, 准教授 (10432634)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 軟骨 / 骨 / ｍRNA / ヌクレオホスミン / 転写後制御 / RNA安定性 |
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| Research Abstract |
We successfully cloned mRNA, which bound to NPM protein in ATDC5 cells (a mouse chondrosarcoma cell line). The gene was found to bind to NPM by REMSA assay, and furthermore, to regulate the growth and differentiation of chondrocytes invivo, utilizing a gene expression and knock-down techniques.
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Research Products
(10 results)
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[Journal Article] Differential expression of vascular endothelial growth factor in high- and low-metastasis cell lines of salivary gland adenoid cystic carcinoma2014
Author(s)
Kondo, S., Mukudai, Y., Soga, D., Nishida, T., Takigawa, M., Shirota, T
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Journal Title
Anticancer Res
Volume: 34(2)
Pages: 671-7
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[Journal Article] Potential anti-osteoporotic effects of herbal extracts on osteoclasts, osteoblasts and chondrocytes in vitro2014
Author(s)
Mukudai, Y, Kondo, S., Koyama, T., Li C., Banka, S., Kogure, A., Yazawa, K., Shintani, S
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Journal Title
BMC Complement Altern Med
Volume: 14
Pages: 29
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[Journal Article] Tumor protein D54 is a negative regulator of extracellular matrix-dependent migration and attachment in oral squamous cell carcinoma-derived cell lines2013
Author(s)
Mukudai, Y., Kondo, S., Fujita, A., Yoshihama, Y., Shirota, T., Shintani, S
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Journal Title
Cellular Oncol
Volume: 36
Pages: 233-245
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