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2013 Fiscal Year Final Research Report

The mechanism of pupil dilation response during cold pressor test

Research Project

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Project/Area Number 23593001
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Surgical dentistry
Research InstitutionNihon University

Principal Investigator

OKA Shunichi  日本大学, 歯学部, 准教授 (20256879)

Co-Investigator(Kenkyū-buntansha) SUZUKI Naoto  日本大学, 歯学部, 教授 (10226532)
OKADA Akiko  日本大学, 歯学部, 准教授 (10434078)
NAKAJIMA Ichiro  日本大学, 歯学部, 教授 (90198078)
OI Yoshiyuki  日本大学, 歯学部, 教授 (60271342)
Project Period (FY) 2011 – 2013
Keywords瞳孔 / 痛み / ストレス / 唾液 / ホルモン
Research Abstract

Dental treatments accompany the stress. This study was evaluated the mechanism of pupil dilation response(PDR) during cold pressor test. One competing hypothesis for the PDR was that PDR was that like the pupillary light reflex, it was not a simple reflexive response.
Cold pressor test increased the value of alpha-amylase at during and 1~3 min, that of cortisol at 10~12 min and 20~22 min after stress. The stress came from cold presser test induced the exciting of sympathetic nerve system using Heart Rate Variability. Pupil dilated immediately after cold presser test, at 30~60 sec.

  • Research Products

    (9 results)

All 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results) Book (1 results)

  • [Journal Article] 高齢者における唾液中αアミラーゼと歯科治療時間について2012

    • Author(s)
      中西穂波、岡俊一、石井宏卓、金博和、見崎徹、大井良之
    • Journal Title

      日歯麻誌

      Volume: 40 Pages: 201-202

    • Peer Reviewed
  • [Journal Article] Alteration of the actin cytoskeleton and localization of theα6β1 andα3 integrins during regeneration of the rat submandibular gland2012

    • Author(s)
      Shimizu O、Shiratsuchi H、Ueda K、Oka S、Oi Y
    • Journal Title

      Arch Oral Biol

      Volume: 57 Pages: 1127-1132

    • Peer Reviewed
  • [Journal Article] Influence of blood pressure on cardio-ankle vascular index (CAVI) examined based on percentage change during general anesthesia2011

    • Author(s)
      Kim B、Takada K、Oka S、Misaki T
    • Journal Title

      Hypertens Res

      Volume: 34 Pages: 779-783

    • Peer Reviewed
  • [Presentation] Human salivaryα-amylase during cold pressor test2013

    • Author(s)
      Oka S、Nakanishi H、Oi Y、Suzuki N
    • Organizer
      FDI 2013 Istanbul Annual World Dental Congress
    • Place of Presentation
      Istanbul、Turkey
    • Year and Date
      2013-08-29
  • [Presentation] 東京都葛飾区における在宅寝たきり老人の歯科治療(第14報)高齢者における唾液量とストレスホルモンの関係2013

    • Author(s)
      鈴木勲、岡俊一、鈴木直人、大井良之他9名
    • Organizer
      日本老年歯科医学会第24回学術大会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2013-06-05
  • [Presentation] 歯科治療時のαアミラーゼの変動2012

    • Author(s)
      岡俊一、中西穂波、里見ひとみ、関野麗子、金博和、鈴木直人、大井良之
    • Organizer
      第22回日本歯科医学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2012-11-10
  • [Presentation] 東京都葛飾区における在宅寝たきり老人の歯科治療(第13報)高齢者における唾液中ストレスホルモンと歯科治療時間について2012

    • Author(s)
      大原義治、岡俊一、他11名
    • Organizer
      日本老年歯科医学会第23回学術大会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2012-06-22
  • [Presentation] Propofol reduces the pupil dilation response to noxious stimulation in humans2012

    • Author(s)
      Oka S、Nakanishi H、Oi Y、Suzuki N
    • Organizer
      15^<th> WFSA World Congress of Anaesthesiologists
    • Place of Presentation
      Buenos Aires、Argentina
    • Year and Date
      2012-03-27
  • [Book] Movement -Related Cortical Potentials Associated with Oral and Facial Functions in Humans2012

    • Author(s)
      Nakajima I、Oka S、Ohba H、Yoshida M
    • Total Pages
      398
    • Publisher
      Applications of EMG in Clinical and Sports Medicine

URL: 

Published: 2015-07-16  

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