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2013 Fiscal Year Final Research Report

Ultra-high speed x-ray movie recording of mandibular movements

Research Project

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Project/Area Number 23593021
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

ZEREDO Jorge  東京医科歯科大学, 歯学部, 非常勤講師 (10363459)

Co-Investigator(Kenkyū-buntansha) ONO Takashi  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30221857)
KUMEI Yasuhiro  東京医科歯科大学, 大学院医歯学総合研究科, 講師 (30161714)
YOSHIDA Noriaki  長崎大学, 大学院医歯学総合研究科, 教授 (40230750)
Co-Investigator(Renkei-kenkyūsha) HASEGAWA Katsuya  独立行政法人宇宙航空開発機構, 宇宙科学研究所, 開発員 (30425780)
Project Period (FY) 2011 – 2013
Keywords姿勢 / 顎運動 / 放射線 / 低重力 / マウス
Research Abstract

This Kakenhi project allowed us to build a device for the study of jaw movements in the mouse through a high-definition x-ray movie system. The use of cineradiographic technology enabled us to study detailed jaw movements in the mouse in a detailed and minimally invasive fashion. In this study, we analyzed postural changes in animals exposed to gravity deceleration. Mice were exposed to partial-gravity deceleration by parabolic flights. As a result, gravity deceleration produced coordinated and generalized extension of head, jaw, spine, and hindlimbs. Joint angles in partial gravity widened about 30% or more in relation to the average 1 g posture. Reflex jaw-opening was observed during gravity deceleration. The magnitude of postural responses was associated positively with gravity deceleration. These results suggest that adaptability to partial gravity may be not only dependent on the partial-gravity level, but also on the rate of gravity change into any given partial-gravity level.

  • Research Products

    (3 results)

All 2014 2013 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Cineradiographic Analysis of Mouse Postural Response to Alteration of Gravity and Jerk (Gravity Deceleration Rate)2014

    • Author(s)
      Hasegawa K, de Campos PS, Zeredo JL, Kumei Y
    • Journal Title

      Life

      Volume: 4(2) Pages: 174-188

    • Peer Reviewed
  • [Journal Article] Behavioral response to partial-gravity conditions in rats2012

    • Author(s)
      Zeredo, JL, Toda K, Matsuura M, Kumei Y
    • Journal Title

      Neuroscience Lett

      Volume: 529(2) Pages: 108-111

    • Peer Reviewed
  • [Presentation] X-ray movie visualization for differential thresholds of mouse adaptation to low gravities2013

    • Author(s)
      Kumei Y, Zeredo JL, Inoue KA, Hasegawa K, Aou S
    • Organizer
      29th Annual Meeting of the ASGSR
    • Place of Presentation
      Hilton Lake Vuena Vista, Orlando FL, USA
    • Year and Date
      2013-11-06

URL: 

Published: 2015-07-16  

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