Study of effective fluoride preparation application method using a saliva fluoride ion concentration in infants

2014 Fiscal Year Final Research Report

• Project/Area Number: 23593047
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: The Nippon Dental University
• Principal Investigator: UCHIKAWA yoshimori 日本歯科大学, 生命歯学部, 教授 (00176679)
• Co-Investigator(Kenkyū-buntansha): IWASAKI Terumi 日本歯科大学, 生命歯学部, 講師 (60515609) ; SHIRASE Toshiomi1 日本歯科大学, 生命歯学部, 准教授 (20237018) ; MITUI Sonoko 日本歯科大学, 生命歯学部, 助教 (10549083)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 幼児 / 唾液 / フッ化物 / 齲蝕予防 / フッ化物製剤

Outline of Final Research Achievements

We measured the fluoride (F) ion concentration in infant saliva and examined the relationship between the F ion concentration and oral hygiene habits. The F ion dynamics in the saliva after the addition of a low-concentration F formulation in the saliva was also examined. We found that the average F ion concentration in Japanese infant saliva was 0.0083 ppmF. This concentration does not reach the minimum concentration necessary for remineralization. Therefore, Japanese infants required an aggressive use of the F formulation. A relationship between the brushing habits and the salivary F ion concentration was observed. The frequency of F formulated toothpaste use raised the F ion concentration in the saliva. When a low-concentration F formulation was introduced into the saliva, cations and proteins were found to decrease the free F ion concentration. According to these results, strategies to maintain the optimal F ion concentration in infant saliva must be developed and implemented.

Free Research Field

小児歯科