2013 Fiscal Year Final Research Report
Effects of resveratrol on salivary secretion
| Project/Area Number |
23593111
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Social dentistry
|
|---|
| Research Institution | Tsurumi University |
|---|
Principal Investigator |
RYO Koufuchi 鶴見大学, 歯学部, 講師 (10298268)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SAITO Ichiro 鶴見大学, 歯学部, 教授 (60147634)
MISHIMA Kenji 昭和大学, 歯学部, 教授 (50275343)
INOUE Hiroko 日本薬科大学, 薬学部, 准教授 (50367306)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | ドライマウス / 口腔乾燥症 / レスベラトロール / 酸化ストレス |
|---|
| Research Abstract |
Dry mouth is a condition associated with reduced salivary secretion. This study was conducted to test of resveratrol affect salivary secretion and glucose and lipid metabolism. Nine patients were given resveratrol orally at a dosage of 76mg/day for 1 month, and salivary secretion and glucose and lipid were analyzed before and after treatments. Homocysteine, HbA1c and IL-6 showed an significant decrease when the amount before intake was compared with that after 1 month. In addition, LDL-C and PWV results showed a significant increase after 1 month.
|
