2013 Fiscal Year Final Research Report
Integrated nutritional epidemiological research for the frailty, osteoporosis and cognitive impairment among the community-dwelling oldest old.
| Project/Area Number |
23617024
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrated Nutrition Science
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ARAI Yasumichi 慶應義塾大学, 医学部, 助教 (20255467)
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| Co-Investigator(Renkei-kenkyūsha) |
IINUMA Toshimitsu 日本大学, 歯学部, 講師 (10246902)
TAKAYAMA Midori 慶應義塾大学, 理工学部, 教授 (10308025)
FUKUDA Ryoko 慶應義塾大学, 環境情報学部, 特任准教授 (80383917)
HIROSE Nobuyoshi 慶應義塾大学, 医学部, 講師 (90142421)
SASAKI Satoshi 東京大学, 医学系研究科, 教授 (70275121)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 栄養疫学 / 健康長寿 / 超高齢者 / ジェロントロジー |
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| Research Abstract |
We have demonstrated a community-based, prospective observational research for dietary habits and health status in the oldest old, 85 years or older, living in Tokyo metropolitan area in Japan. We evaluated risk factors which related to newly developed cognitive impairment, fractures, and institutionalization during three years using multivariate logistic analyses. Low MMSE score, ADL disability, and slow gait speed appeared to be risk for newly developed cognitive impairment. Women, low MMSE score, history of stroke and fracture, and high hemoglobin A1c appeared to be risk for newly developed fractures. Women and slow gait speed seemed to be risk factors for newly institutionalization.
We also have validated a brief-type dietary history questionnaire (BDHQ) compared with three-day dietary records and showed that regarding some specific nutrients or foods, BDHQ could be a useful tool for epidemiologic research even in the oldest old.
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