2013 Fiscal Year Final Research Report

Elucidation of the contribution of lymphatic transport to the intestinal absorption of various food factors

Research Project

Project/Area Number	23617032
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Integrated Nutrition Science
Research Institution	Kinki University
Principal Investigator	MUROTA Kaeko 近畿大学, 理工学部, 講師 (40294681)
Co-Investigator(Renkei-kenkyūsha)	TAKAHASHI Nobuyuki 京都大学, 大学院農学研究科, 助教 (50370135) MURAKAMI Megumi 同志社女子大学, 生活科学部, 准教授 (80340769)
Project Period (FY)	2011 – 2013
Keywords	腸管吸収 / リンパ系輸送 / カイロミクロン / フラボノイド / ビタミンE / プロビタミンAカロテノイド
Research Abstract	We investigated the contribution of lymphatic transport to the intestinal absorption of various food factors, including vitamin E, carotenoids and flavonoids. Lymphatic transport level of highly hydrophobic vitamins was effectively enhanced when they were solubilized in the intestinal fluid, whereas a quercetin glucoside, a major flavonoid glycoside, was less absorbed when administrated with fatty acids simultaneously. It was also suggested that a relatively hydrophobic methoxyflavonoid was transported in the lymph at the higher level than quercetin.