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2012 Fiscal Year Final Research Report

Sugar Chain Computer-Analyzing Computational Power of the 3rdBiological Chain Material

Research Project

  • PDF
Project/Area Number 23650069
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent informatics
Research InstitutionTokyo Institute of Technology

Principal Investigator

YAMAMURA Masayuki  東京工業大学, 大学院・総合理工学研究科, 教授 (00220442)

Co-Investigator(Renkei-kenkyūsha) SUZUKI Yasuhiro  名古屋大学, 情報文化学部, 准教授 (50292983)
Project Period (FY) 2011 – 2012
Keywords知能情報処理 / 人工化学 / 糖鎖計算 / 文脈自由言語 / 糖鎖 / 糖転移酵素 / ゴルジ装置
Research Abstract

Sugar chain is called the third biological chain material which follows nucleotide and protein. It has important function such as an identifier of a cell for example. Sugar chain has unique tree structure while nucleotide and protein has linear form and is synthesized by unique process of multiple stages without any templates. We regard sugar chain formation as an information processing and analyzed its competence. Firstly, we made a simulator for sugar chain formation with stochastic artificial chemistry. Then, we tried to generate cellular identifier patterns with three stage process simulation. As the result, sugar chain formation can accept any context free language, and three separate stages are critical to generate a certain cellular identifier pattern efficiently.

  • Research Products

    (6 results)

All 2013 2012

All Journal Article (6 results) (of which Peer Reviewed: 2 results)

  • [Journal Article] Harness the Nature for Computation,Natural Computing and Beyond2013

    • Author(s)
      Y.Suzuki
    • Journal Title

      Springer Verlag

      Volume: vol.6 Pages: 47-70

  • [Journal Article] Design and Control of Synthetic Biological Systems2013

    • Author(s)
      Ryoji Sekine and Masayuki Yamamura
    • Journal Title

      Natural Computing and Beyond

      Volume: vol.6 Pages: 104-114

    • Peer Reviewed
  • [Journal Article] 周波数特性を用いた振動する人工遺伝子回路の自動設計2013

    • Author(s)
      林孝文、山村雅幸
    • Journal Title

      計測自動制御学会第40回知能システムシンポジウム資料集

      Pages: 211-216

  • [Journal Article] Design strategy for an initial state-independent diversity generator2012

    • Author(s)
      Ryoji Sekine, Daisuke Kiga, and Masayuki Yamamura
    • Journal Title

      Chem-Bio Informatics Journal

      Volume: vol.12 Pages: 39-49

    • Peer Reviewed
  • [Journal Article] Tunability of the ratio of cell states after the synthetic diversification by the diversity generator2012

    • Author(s)
      Ryoji Sekine,Masayuki Yamamura,Masami Hagiya,and Daisuke Kiga
    • Journal Title

      Communicative and Integrative Biology

      Volume: vol.5,no.4

  • [Journal Article] Behaviors of Chemical Reactions with Small Number of Molecules, Lecture Notes in Computer Science2012

    • Author(s)
      Y. Suzuki
    • Journal Title

      Springer Verlag

      Volume: vol.5777 Pages: 394-401

URL: 

Published: 2014-09-25  

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