2012 Fiscal Year Final Research Report
Establishment of the diagnostics of Alzheimer' s disease using A・43
| Project/Area Number |
23650185
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
SAITO Takashi 独立行政法人理化学研究所, 神経蛋白制御研究チーム, 副チームリーダー (90360552)
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| Project Period (FY) |
2011 – 2012
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| Keywords | アルツハイマー病 / トランスレーショナルリサーチ / 早期診断 |
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| Research Abstract |
Establishment of an early diagnosis for Alzheimer’s disease (AD) is one of the important missions in an aging society. Recently, we found that Ass43 is generated under an age-dependent manner, thereby it might be a good candidate as a marker for an early diagnosis of AD. Herein, we established a high-sensitive and quantitative method to detect Ass43 specifically in the sample from mice and human materials. Finally, we concluded that Ass43 has a potent pathogenicity, and would be an useful candidate for an early diagnosis for AD.
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Research Products
(9 results)
