2012 Fiscal Year Final Research Report
Participation of the oligodendrocyte/oligodendrocyte precursor cell in the morbidity of schizophrenia
| Project/Area Number |
23650186
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Tohoku University |
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Principal Investigator |
OSUMI Noriko 東北大学, 大学院・医学系研究科, 教授 (00220343)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 統合失調症 / オリゴデンドロサイト前駆細胞 / オリゴ新生 / 神経新生 / プレパル ス抑制 |
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| Research Abstract |
We examined relationship between defects in prepulse inhibition and OPC-genesis. Almost all OPCs expressed Fabp7, whereas about 7% of did Pax6. Significant change was not detected in OPC-genesis of Fabp7 KO mice and Pax6 mutant mice.
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Research Products
(26 results)
