Exploring quantitative association between neural and hemodynamic responses using MEG-NIRS simultaneous measurement

2012 Fiscal Year Final Research Report

• Project/Area Number: 23650217
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Fusional basic brain science
• Research Institution: Jichi Medical University
• Principal Investigator: DAN Ippeita 自治医科大学, 医学部, 准教授 (20399380)
• Project Period (FY): 2011 – 2012
• Keywords: NIRS / MEG / マルチモーダルイメージング / 同時計測 / 一般線形モデル

Research Abstract

We introduced adaptive methods to find the optimal HRF for temporal analysis of NIRS data. Application of the GLM with regression to a temporally optimized HRF on the functional activation data during different language tasks revealed

Research Products

• [Journal Article] (2013)
  • Author(s): Okamoto M, *Dan I
  • Journal Title: Seminars in Cell and Developmental Biology Volume: 24(3) Pages: 247-55
  • Peer Reviewed
• [Journal Article] Stable and convenient spatial registration of stand-alone NIRS data through anchor-based probabilistic registration. (2012)
  • Author(s): Tsuzuki D, Cai D S, Haruka D, Kyutoku Y, Fujita A, Watanabe E, *Dan I
  • Journal Title: Neuroscience Research. Volume: 72 Pages: 163-171
  • Peer Reviewed
• [Journal Article] Multichannel fNIRS assessment of overt and covert confrontation naming. (2012)
  • Author(s): Moriai-Izawa A, Dan H, *Dan I, Sano T, Oguro K, Yokota H, Tsuzuki D, Watanabe E.
  • Journal Title: Brain and Language Volume: 121(3) Pages: 185-93
  • Peer Reviewed
• [Journal Article] Effect of anesthesia on trigeminal somatosensory evoked magnetic fields. (2012)
  • Author(s): Otsuka T, Dan H, *Dan I, Sase M, Sano T, Tsuzuki D, Sasaguri K, Okada N, Kusama M, Jinbu Y, Watanabe E
  • Journal Title: Journal of Dental Research. Volume: 91(12) Pages: 1196-201
  • Peer Reviewed
• [Journal Article] Right prefrontal activation as a neuro-functional biomarker for monitoring acute effects of methylphenidate in ADHD children: An fNIRS study. (2012)
  • Author(s): Monden Y, Dan H, Nagashima M, *Dan I, Tsuzuki D, Kyutoku Y, Gunji Y, Yamagata T, Watanabe E, Momoi M Y
  • Journal Title: NeuroImage:Clinical. Volume: 1(1) Pages: 131-140
  • Peer Reviewed
• [Journal Article] Validating atlas-guided DOT: a comparison of diffuse optical tomography informed by atlas and subject-specific anatomies. (2012)
  • Author(s): Cooper R J, Caffini M, Dubb J, Custo A, Tsuzuki D, Fischl B, Wells W, Dan I, Boas D A
  • Journal Title: NeuroImage. Volume: 62(3) Pages: 1999-2006
  • Peer Reviewed
• [Journal Article] Language-specific cortical activation patterns for verbal fluency tasks in Japanese as assessed by multichannel functional near-infrared spectroscopy.
  • Author(s): Dan H, *Dan I, Sano T, Kyutoku Y, Oguro K, Yokota H, Tsuzuki D, Watanabe E.
  • Journal Title: Brain and Language
  • Peer Reviewed
• [Presentation] Spatial and temporal considerations for achieving intermodal cross-referencing of fNIRS data. (2012)
  • Author(s): Dan, I.
  • Organizer: "UK/JP Workshop for Multimodal Imaging" by The UK Embassy of Tokyo, and The Royal Society
  • Place of Presentation: Kavli Center, UK
  • Year and Date: 2012-02-29
• [Presentation] Adaptive Hemodynamic Response Function to Optimize Differential Temporal Information of Hemoglobin Signals in Functional Near-Infrared Spectroscopy.
  • Author(s): Sano T, Tsuzuki D, *Dan I, Dan H, Yokota H, Oguro K, Watanabe E
  • Organizer: Complex Medical Engineering (CME)
• [Remarks]
  • URL: http://www.brain-lab.jp/
• [Patent(Industrial Property Rights)] 経頭蓋脳機能解析方法 (2012)
  • Inventor(s): 檀一平太、續木大介、渡辺英寿
  • Industrial Property Rights Holder: 同上
  • Industrial Property Number: 特願 2012-95838
  • Filing Date: 2012-04-19