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2012 Fiscal Year Final Research Report

Development of drug carrier for bone regeneration

Research Project

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Project/Area Number 23650282
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biological material science
Research InstitutionTohoku University

Principal Investigator

ANADA Takahisa  東北大学, 大学院・歯学研究科, 准教授 (30398466)

Co-Investigator(Kenkyū-buntansha) SUZUKI Osamu  東北大学, 大学院・歯学研究科, 教授 (60374948)
Project Period (FY) 2011 – 2012
Keywords再生医工学材料 / 骨再生 / ドラッグデリバリー
Research Abstract

Novel calcium phosphate-binding lipids were synthesized. The polymer modified lipids were incorporated efficiently into liposomes. We found that the calcium phosphate binding and drug encapsulation efficiencies of the polymer modified liposomes were higher than those of the unmodified liposomes.

  • Research Products

    (4 results)

All 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Remarks (1 results)

  • [Journal Article] Labile Zn ions on octacalcium phosphate-derived Zn-containing hydroxyapatite2013

    • Author(s)
      Y Honda, T Anada, S Morimoto, O Suzuki
    • Journal Title

      Appl Sur Sci

      Volume: 273 Pages: 343-348

    • URL

      http://dx.doi.org/10.1016/j.apsusc.2013.02.040

    • Peer Reviewed
  • [Journal Article] Comparative study on in vitro biocompatibility of synthetic octacalcium phosphate and calcium phosphate ceramics used clinically2012

    • Author(s)
      S Morimoto, T Anada, Y Honda, O Suzuki
    • Journal Title

      Biomed Mater

      Volume: 7 Pages: 045020

    • DOI

      doi:10.1088/1748-6041/7/4/045020

    • Peer Reviewed
  • [Journal Article] Structural, morphological and surface characteristics of two types of octacalcium phosphate-derived fluoride-containing apatitic calcium phosphates2012

    • Author(s)
      Y Shiwaku, T Anada, H Yamazaki, Y Honda, S Morimoto, K Sasaki, O Suzuki
    • Journal Title

      Acta Biomater

      Volume: 8 Pages: 4417-4425

    • DOI

      doi:10.1016/j.actbio.2012.07.041.

    • Peer Reviewed
  • [Remarks]

    • URL

      http://www.cfe.dent.tohoku.ac.jp/

URL: 

Published: 2014-09-25   Modified: 2015-11-04  

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