2012 Fiscal Year Final Research Report
Acquired Disease Treatment by Epigenetics Engineering
| Project/Area Number |
23650291
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | Tokyo Metropolitan University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | エピジェネティクス / DNA メチル化 / ヒストン修飾 / クロマチン |
|---|
| Research Abstract |
In this reserach, to establish epigenetics engineering for cellular differentiation, we have designed new biodegradable nanospheres for controlled release. A prepared new carrier was delivered into human leukemia HL-60 cells, resulting in significant differentiation to granulocytic cells.
|
