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2012 Fiscal Year Final Research Report

Study on the mechanism for suppression of myopenia by exercise through functional RNA

Research Project

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Project/Area Number 23650402
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionUniversity of Tsukuba

Principal Investigator

TAKEMASA Tohru  筑波大学, 体育系, 教授 (50236501)

Project Period (FY) 2011 – 2012
Keywords運動生理学 / 分子生物学 / 筋萎縮 / 筋肥大 / マイクロRNA
Research Abstract

In this study, we focused on functional RNA expression in muscle during mechanical overload to explain a part of mechanisms of muscle hypertrophy. As a result, we got some data suggesting that mi-21 (micro-RNA) could be an important functional RNA to induce muscle hypertrophy.

  • Research Products

    (7 results)

All 2013 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results)

  • [Journal Article] Reduction of ribosome biogenesis with activation of the mTOR pathway in denervated atrophic muscle2012

    • Author(s)
      Masanao Machida, Kohei Takeda, Hiroyuki Yokono, Sachiko Ikemune, YukaTaniguchi, Hidenori Kiyosawa, and Tohru Takemasa
    • Journal Title

      J Cell Physiol

      Volume: 227 Pages: 1569-1576

    • Peer Reviewed
  • [Journal Article] Possible involvement of microRNA-21 in skeletal muscle hypertrophy2012

    • Author(s)
      Tohru Takemasa, Yousuke Abe, Chiaki Kumagai, Hidenori Kiyosawa
    • Journal Title

      Adv. Exerc. Sports Physiol

      Volume: 18 Pages: 5-15

    • Peer Reviewed
  • [Presentation] シトルリン摂取による廃用性筋萎縮の抑制効果の検討2013

    • Author(s)
      福田麦穂, 武政徹
    • Organizer
      第157回日本体力医学会関東地方会
    • Place of Presentation
      東京
    • Year and Date
      2013-03-30
  • [Presentation] High-Frequency Acupuncture Represses the Atrophy of Fast-Fiber Rich Skeletal Muscle.2012

    • Author(s)
      Shin Fujimaki, Masanao Machida, Kohei Takeda, Tohru Takemasa
    • Organizer
      59thAnnual Meeting of American College of Sports Medicine in San Francisco
    • Place of Presentation
      California, USA
    • Year and Date
      2012-06-01
  • [Presentation] 筋萎縮時におけるリボソームRNAの合成とmTOR経路の変化2012

    • Author(s)
      町田正直,武田紘平,横野裕行,武政徹
    • Organizer
      2012年生体運動研究合同班会議
    • Place of Presentation
      茨城
    • Year and Date
      2012-01-06
  • [Presentation] 除神経モデルを用いた鍼通電刺激の筋萎縮抑制効果の検討2011

    • Author(s)
      藤巻慎, 町田正直, 武田紘平, 武政徹
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      山口
    • Year and Date
      2011-09-17
  • [Presentation] 筋萎縮時におけるリボソームRNA合成低下を引き起こす因子の検討.2011

    • Author(s)
      町田正直, 武田紘平, 横野裕行, 池宗佐知子, 北岡祐, 大野秀樹, 武政徹
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      山口
    • Year and Date
      2011-09-17

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Published: 2014-09-25  

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