2013 Fiscal Year Final Research Report
Estimation of health status by exhaled gas analysis
Project/Area Number |
23650427
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Applied health science
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Research Institution | Hirosaki University |
Principal Investigator |
NAKAJI Shigeyuki 弘前大学, 医学(系)研究科(研究院), 教授 (10192220)
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Co-Investigator(Kenkyū-buntansha) |
MATSUZAKA Masashi 弘前大学, 大学院医学研究科, 講師 (70431434)
DANJO Kazuma 弘前大学, 大学院医学研究科, 助教 (90463760)
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Project Period (FY) |
2011 – 2012
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Keywords | 呼気 / 水素 / メタン / 一酸化炭素 / 好中球機能 / 過敏性腸症候群 / ライフスタイル / 活性酸素 |
Research Abstract |
Following results were obtained from the investigation between exhaled gas, irritable bowel syndrome (IBS), neutrophil functions and lifestyles among 992 adults. 1. IBS group - significantly high level of exhaled hydrogen concentration was observed in females with IBS-D (IBS with diarrhea) compared with females in normal group, IBS with constipation or IBS with both diarrhea and constipation. 2. Negative correlations were observed between serum opsonic activity (Luminol-dependent chemiluminescence) and exhaled carbon monoxide in both genders. In addition, positive correlation was observed between serum opsonic activity (Lucigenin-dependent chemiluminescence) and exhaled carbon monoxide in females. 3. As for the association between exhaled carbon monoxide and age, BMI, the amount of alcohol consumption and exercise habit, no significant correlations were observed in any items. Therefore, certain relationships were found between exhaled gas and diseases, health status and lifestyle.
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Research Products
(5 results)
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[Journal Article] Prevalence of irritable bowel syndrome and its relation to lifestyle and depression quotient in a Japanese general population2011
Author(s)
Kumeta K, Danjo K, Matsuzaka M, Takahashi I, Watanabe K, Iwane K, Tsuya, R, Umeda T, Sato K, Fukuda S, Nakaji S
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Journal Title
Hirosaki Med J
Volume: 62
Pages: 144-65
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