The new standard for assessment of visceral adipose tissue

2013 Fiscal Year Final Research Report

• Project/Area Number: 23650429
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Applied health science
• Research Institution: University of Tsukuba
• Principal Investigator: TANAKA Kiyoji 筑波大学, 体育系, 教授 (50163514)
• Co-Investigator(Kenkyū-buntansha): NAKATA Yoshio 筑波大学, 医学医療系, 准教授 (00375461)
• Co-Investigator(Renkei-kenkyūsha): NUMAO Shigeharu 早稲田大学, スポーツ科学学術院, 助教 (90454074)
• Project Period (FY): 2011 – 2013
• Keywords: 内臓脂肪体積 / multiple-slice法 / MRI

Research Abstract

The accuracy of a depicting visceral adipose tissue (VAT) accumulation is of importance for future obesity related diseases. In this thesis, we aimed to clarify the influence of single-slice image measurement sites on VAT volume and changes in VAT volume and to determine whether the measurement site affects the relationship between the single-slice image of the VAT area and cardiovascular disease (CVD) risk factors. The results suggest that using a single-slice image at 5-6 cm above L4-L5 has a much greater detecting power for estimating VAT volume and changes than a single-slice image at L4-L5.
These results suggest that future studies should consider choosing a single-slice image located 5-6 cm above L4-L5 instead of (or in addition to) the L4-L5 image to examine the association with CVD risk factors.

Research Products

• [Journal Article] NUDT3 rs206936 is associated with body mass index in obese Japanese women (2013)
  • Author(s): Kitamoto A, Kimoto T, Mizusawa S, Teranishi H, So R, Matsuo T, Nakata Y, Hyogo H, Ochi H, Nakamura T, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaquchi K, Yamada K, Hanafusa T, Okikawa S, Sakata T, Tanaka K, Matsuzawa Y, Nako K, Sekine A, Hotta K
  • Journal Title: Endocr J Volume: 60(8) Pages: 991-1000
  • DOI: 10.1507/endocrj.EJ13-0100
  • Peer Reviewed
• [Journal Article] Visceral Adipose Tissue Volume Estimated at Imaging Sites 5-6cm Above L4-L5 Is Optimal for Predicting Cardiovascular Risk Factors in Obese Japanese Men (2012)
  • Author(s): So R, Sasai H, Matsuo T, Tsujimoto T, Eto M, Saotome K, Tanaka K
  • Journal Title: Tohoku J Exp Med Volume: 227(4) Pages: 297-305
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/22850595
  • Peer Reviewed
• [Journal Article] Best single-slice measurement site for estimating visceral adipose tissue volume after weight loss in obese (2012)
  • Author(s): So R, Matsuo T, Sasai H, Eto M, Tsujimoto T, Saotome K, Tanaka K
  • Journal Title: Japanese men. Nutrition and Metabolism Volume: 9(1) Pages: 56
  • DOI: 10.1186/1743-7075-9-56
  • Peer Reviewed
• [Journal Article] Multiple-slice magnetic resonance imaging can detect visceral adipose tissue reduction more accurately than single-slice imaging (2012)
  • Author(s): So R, Sasai H, Matsuo T, Tsujimoto T, Eto M, Saotome K, Tanaka K
  • Journal Title: European Journal of Clinical Nutrition Volume: 66(12) Pages: 1351-1355
  • DOI: 10.1038/ejcn.2012.147
  • Peer Reviewed
• [Presentation] 内臓脂肪蓄積と形態指標の関連 : 肥満男性における年代別検討 (2013)
  • Author(s): 田中喜代次, 辻本健彦, 蘇リナ
  • Organizer: 第20回日本未病システム学会学術集会
  • Place of Presentation: 学術総合センター(東京)
  • Year and Date: 20131109-10
• [Presentation] 減量が肥満男性の筋力に及ぼす影響 (2013)
  • Author(s): 田中喜代次, 金甫建, 辻本健彦, 蘇リナ
  • Organizer: 第21回日本運動生理学会大会
  • Place of Presentation: 東京国際大学(埼玉県)
  • Year and Date: 20130727-28
• [Presentation] Multiple-slice 法を用いた腹部脂肪変化の検討 (2013)
  • Author(s): 蘇リナ, 辻本健彦, 金甫建, 田中喜代次
  • Organizer: 第21回日本運動生理学会大会
  • Place of Presentation: 東京国際大学(埼玉県)
  • Year and Date: 20130727-28
• [Presentation] Acceleration training for improving physical fitness and weight loss in obese women (2013)
  • Author(s): So R, Eto M, Tujimoto T, Tanaka K
  • Organizer: 18th annual congress of the European College of Sport Science
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 20130626-29