2012 Fiscal Year Final Research Report
Disease-specific intestinal nutrient sensing mechanismand the development of special nutrition foods
| Project/Area Number |
23650482
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | The University of Tokushima |
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Principal Investigator |
YAMAMOTO Hironori 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (60314861)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 特殊栄養食品 |
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| Research Abstract |
In this study, we established disease-specific intestinal nutrient sensing mechanism and a basis for the development of special nutritious food. I identified renal disease-specific nutrient sensor genes and gene database using DNA microarray analysis. In addition, administration of phosphorus restricted diet to renal failure animal model, found that to prevent the development of ectopic calcification and calcium metabolism abnormality, also effective in the prevention of renal anemia.
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Research Products
(12 results)
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[Journal Article] Dietary phosphate restriction ameliorates endothelial dysfunction in adenine-induced kidney disease rats2012
Author(s)
Van TV, Watari E, Taketani Y, Kitamura T, Shi ota A, Tanaka T, Tanimura A, Harada N, Nakaya Y, Yamamoto H, Miyamoto K, Takeda E
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Journal Title
J Clin Biochem Nutr
Volume: 51(1)
Pages: 27-32
DOI
Peer Reviewed
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