2012 Fiscal Year Final Research Report

Construction of the homing cells harboring sensitive fluorescence probes for detection of environmental pollutants

Research Project

Project/Area Number	23651086
Research Category	Grant-in-Aid for Challenging Exploratory Research
Allocation Type	Multi-year Fund
Research Field	Environmental technology/Environmental materials
Research Institution	大学共同利用機関法人自然科学研究機構(岡崎共通研究施設) (2012) National Institutes of Natural Sciences Okazaki Research Facilities (2011)
Principal Investigator	AONO Shigetoshi 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 教授 (60183729)
Project Period (FY)	2011 – 2012
Keywords	環境技術 / 生物物理 / 蛋白質 / 生体機能利用
Research Abstract	In this work, the construction of FRET-type fluorescence probes using HRM（heme regulatory motif）or transition metal ions binding protein SmtA was tried.Structural and functional characterization of the transition metal ion-containing chemotaxis signal transducer protein was carried out to obtain basic information for the construction of homing cells that can swarm spontaneously toward transition metal ions.