2012 Fiscal Year Final Research Report
Novel Control of Stereochemistry Using Photo Irradiation
| Project/Area Number |
23655078
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Chiba University |
|---|
Principal Investigator |
ARAI Takayoshi 千葉大学, 大学院・理学研究科, 教授 (80272483)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 触媒・化学プロセス / 光反応 / 不斉合成・反応 / 錯体化学 / 合成化学 |
|---|
| Research Abstract |
In this project, the metal complex-catalyzed asymmetric reactions were combined with photo-irradiation for supplying novel chiral compounds. For an example, the Friedel-Crafts/Henry reaction of indoles, nitroalkenes, and aldehydes, gave the three components coupling compounds having new contiguous stereogenic centers by the combination use of photo-isomerization of trans-nitroalkenes to the cis-nitoroalkenes. The method was also applicable to the [3+2]-cycloaddition of nitroalkenes with iminoesters. Moreover, the photo-irradiation was effective for controlling the activities of metal-proton cooperative catalyst.
|
Research Products
(57 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Construction of Multiple Stereogenic Centers on Indoles and Pyrroles2011
Author(s)
Takayoshi Arai, AtsukoAwata, Makiko Wasai, Naota Yokoyama, Satomi Oyama, and Hiromichi Fujino
Organizer
The 6th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-6)/The 2nd New Phase International Conference on Cutting-Edge Organic Chemistry in Asia (NICCEOCA-2)
Place of Presentation
Hong Kong
Year and Date
20111211-15
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
