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2013 Fiscal Year Final Research Report

CMOS-based flexible brain stimulation / measurement device

Research Project

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Project/Area Number 23656241
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Electron device/Electronic equipment
Research InstitutionNara Institute of Science and Technology

Principal Investigator

TOKUDA Takashi  奈良先端科学技術大学院大学, 物質創成科学研究科, 准教授 (50314539)

Co-Investigator(Renkei-kenkyūsha) OHTA Jun  奈良先端科学技術大学院大学, 物質創成科学研究科, 教授 (80304161)
SASAGAWA Kiyotaka  奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (50392725)
NODA Toshihiko  奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (20464159)
Project Period (FY) 2011 – 2013
Keywordsバイオデバイス / バイオセンシング / 脳刺激計測 / CMOS / 生体埋め込みデバイス
Research Abstract

A CMOS-based implantable flexible neural stimulation / measurement device was proposed and demonstrated. The most important feature of the device is its "Multi-chip architecture".
We design a small-sized, intelligent neural interface devices ("Unit chip") and aligned them on a flexible substrate. It enables a neural stimulation / measurement device with intelligent functionality and flexibility to fit a curved tissue.We designed a CMOS unit chip and fabricated a flexible neural stimulation / measurement device for feasibility study, and obtained promising results.

  • Research Products

    (16 results)

All 2014 2013 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (12 results) (of which Invited: 6 results)

  • [Journal Article] Performance improvement and functionalization of an electrode array for retinal prosthesis by iridium oxide coating and introduction of smart-wiring technology using CMOS microchips2014

    • Author(s)
      T. Noda, K. Sasagawa, T. Tokuda, Y. Terasawa, H. Takashiro, H. Kanda, T. Fujikado, and J. Ohta
    • Journal Title

      Sensors and Actuators A : Physcal

      Volume: 211 Pages: 27-37

    • Peer Reviewed
  • [Journal Article] A CMOS optoelectronic neural interface device based on an image sensor with on-chip light stimulation and extracellular neural signal recording for optogenetics2013

    • Author(s)
      Y. Sawadsaringkarn, T. Miyatani, T. Noda, K. Sasagawa, T. Tokuda, and J. Ohta
    • Journal Title

      ITE Transactions on Media Technology and Applications

      Volume: 1(2) Pages: 184-189

    • Peer Reviewed
  • [Journal Article] Sputtering Condition Optimization of Sputtered IrOx and TiN Stimulus Electrodes for Retinal Prosthesis2013

    • Author(s)
      Yi-Li Pan, T. Noda, K. Sasagawa, T. Tokuda, and J. Ohta
    • Journal Title

      IEEJ Transaction on Electrical and Electronic Engineering

      Volume: 8(3) Pages: 310-312

    • Peer Reviewed
  • [Journal Article] A Smart Electrode Array Device with CMOS Multi-Chip Architecture for Neural Interface2012

    • Author(s)
      T. Noda, K. Sasagawa, T. Tokuda, Y. Terasawa, H. Tashiro, H. Kanda, T. Fujikado and J. Ohta
    • Journal Title

      Electronics Letters

      Volume: 48(21) Pages: 1328-1329

    • Peer Reviewed
  • [Presentation] CMOS ベースマイクロバイオメディカルフォトニックデバイスの研究開発2014

    • Author(s)
      徳田 崇, 他
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      新潟大学五十嵐キャンパス
    • Year and Date
      2014-03-20
    • Invited
  • [Presentation] AC 駆動型人工視覚向け網膜刺激デバイスの駆動検証2014

    • Author(s)
      藤沢 匠, 他
    • Organizer
      応用物理学会春季学術講演会
    • Place of Presentation
      青山学院大学相模原キャンパス
    • Year and Date
      2014-03-17
  • [Presentation] CMOS イメージセンサをベースとした生体埋め込みデバイス2014

    • Author(s)
      徳田 崇, 他
    • Organizer
      集積光デバイスと応用技術時限研究専門委員会
    • Place of Presentation
      鬼怒川温泉ホテル
    • Year and Date
      2014-01-31
    • Invited
  • [Presentation] CMOS-based Bio- Implantable Neural Observation and Stimulation Device2013

    • Author(s)
      T. Tokuda
    • Organizer
      International Workshop on Biomedical Engineering Translational Research
    • Place of Presentation
      National Chiao Tung University, Hsinchu City, Taiwan
    • Year and Date
      2013-12-10
    • Invited
  • [Presentation] Device Packaging of CMOS-Based Optoelectronic Neural Interface Device for in Vitro and in Vivo Optogenetics2013

    • Author(s)
      T. Tokuda, et al
    • Organizer
      International IEEE EMBS Conference on Neural Engineering
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2013-11-07
  • [Presentation] Intelligent Retinal Prosthetic Device Employs Smart Electrode Array Integrated with CMOS Microchips2013

    • Author(s)
      T. Noda, et al
    • Organizer
      International Conference on BioSensors, BioElectronics, BioMedical Devices
    • Place of Presentation
      BioMEMS/NEMS and Applications 2013
    • Year and Date
      2013-10-30
  • [Presentation] CMOS チップ搭載型生体埋め込みデバイス-エレクトロニクスの新しいバイオ・医療応用に向けて2013

    • Author(s)
      徳田 崇
    • Organizer
      応用物理学会関西支部平成25年度第2回講演会「関西のグリーン・バイオエレクトロニクス研究の現状と若手からの発信」
    • Place of Presentation
      奈良先端科学技術大学院大学
    • Year and Date
      2013-10-09
  • [Presentation] Optoelectronics Devices for Biomedical Applications2013

    • Author(s)
      T. Tokuda
    • Organizer
      The 10th Conference on Lasers and Electro-Optics Pacific Rim (CLEOPR2013)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2013-07-02
    • Invited
  • [Presentation] Microelectronics-based Implantable Devices for Bio-Medical ApplicationsMicroelectronics-based Implantable Devices for Bio-Medical Applications2012

    • Author(s)
      T. Tokuda
    • Organizer
      IEEEPrimeAsia Conference 2012
    • Place of Presentation
      Hyderabad, INDIA
    • Year and Date
      2012-12-06
  • [Presentation] CMOS 技術を用いた生体埋め込み対応バイオデバイス2012

    • Author(s)
      徳田 崇, 他
    • Organizer
      第25回回路とシステムワークショップ
    • Place of Presentation
      淡路夢舞台, 兵庫県
    • Year and Date
      2012-07-30
    • Invited
  • [Presentation] CMOS チップを搭載した刺入型刺激・計測デバイスの作製2012

    • Author(s)
      東丸 幸江, 他
    • Organizer
      第59回応用物理学関係連合講演会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2012-03-16
    • Invited
  • [Presentation] CMOS チップ搭載インテリジェント生体インターフェースデバイス2011

    • Author(s)
      野田 俊彦, 他
    • Organizer
      電気学会E 部門バイオ・マイクロシステム研究会
    • Place of Presentation
      東京工業大学
    • Year and Date
      2011-06-30

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Published: 2015-06-25  

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