2012 Fiscal Year Final Research Report
Molecular physiological mechanism for discrimination of multipleneural signaling in neural circuit
| Project/Area Number |
23657004
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Konan University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 線虫 / C. elegans / 温度応答 / 神経回路 / カルシウムイメージング |
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| Research Abstract |
To identify molecular and physiological mechanisms for discrimination of neuralinformation, we used simple local neural circuit underlying temperature sensation andprocessing. We utilized molecular genetics, behavioral analysis and optical imaging andmanipulation of neural activity. W found that neural coding for discrimination of multipletemperatures signaling through glutamate neurotransmission, molecular mechanism fordiscrimination of sensations, and localization mechanisms of synapses involved ininformation discrimination in axon.
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[Journal Article] A Novel and Conserved Protein AHO-3 IsRequired for Thermotactic PlasticityAssociated with Feeding States inCaenorhabditis elegans2012
Author(s)
Nishio, N., Mohri-Shiomi, A., Nishida,Y., Hiramatsu, N., Kodama, E., Kimura, K., Kuhara A., Mori, I
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Journal Title
Genes to Cells
Volume: 17(5)
Pages: 365-386
DOI
Peer Reviewed
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[Journal Article] Novel and conserved proteinTTX-8/Macoilin is required for diverseneuronal functions in C.2011
Author(s)
Miyara, A., Ohta, A., Okochi, Y.,Tsukada, Y., Kuhara, A., Mori, I.
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Journal Title
elegansPLoS Genetics
Volume: 7(5)
Pages: 1-14
DOI
Peer Reviewed
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