2012 Fiscal Year Final Research Report
Search of receptor for a novel neuropeptide in the hypothalamus
| Project/Area Number |
23657057
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Hiroshima University |
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Principal Investigator |
UKENA Kazuyoshi 広島大学, 大学院・総合科学研究科, 准教授 (10304370)
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| Co-Investigator(Kenkyū-buntansha) |
SAITO Yumiko 広島大学, 大学院・総合科学研究科, 教授 (00215568)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 受容体 / 神経ペプチド / カルシウムイメージング / 培養細胞 |
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| Research Abstract |
Recently, we identified a novel hypothalamic gene in the avian and mammalian brains. We predict that this novel gene encodes a neuropeptide and this peptide is involved in the energy homeostasis. The identification of the specific receptor is essential to elucidate the physiological roles of the neuropeptide. In this study, we soughtthe receptor for the neuropeptide by signal transduction assay . Unfortunately , we could not find the specific receptor in this study .
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[Journal Article] Identification, localization and function of a novel neuropeptide, 26RFa, and its cognate receptor, GPR103, in the avian hypothalamus.2013
Author(s)
Ukena K, Tachibana T, Tobari Y, Leprince J, Vaudry H, Tsutsui K.
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Journal Title
Gen. Comp. Endocrinol.
Pages: in press
Peer Reviewed
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[Journal Article] Identification, localisation and functional implication of 26RFa orthologue peptide in the brain of zebra finch (Taeniopygia guttata)2011
Author(s)
Tobari Y, Iijima N, Tsunekawa K, Osugi T, Haraguchi S, Ubuka T, Ukena K, Okanoya K, Tsutsui K, Ozawa H.
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Journal Title
J. Neuroendocrinol
Volume: 23
Pages: 791-803
Peer Reviewed
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