2012 Fiscal Year Final Research Report
Clarification of the molecular mechanisms that degitize Wnt signaling.
| Project/Area Number |
23657132
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Cell biology
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
ISHITANI Tohru 九州大学, 生体防御医学研究所, 准教授 (40448428)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | Wntシグナル |
|---|
| Research Abstract |
During axis-formation in vertebrate tissues, cells sense the concentration of Wnt ligands and convert its information into the digital information that directs the regulation of selective gene expression. In this study, we investigated this Wnt signaling-degitizing system and found that DP1 protein is involved in this system. We also generated the new experimental systems for observing Wnt signaling activity in living animals.
|
