2012 Fiscal Year Final Research Report
Functional analysis of the autophagy specific to filamentous fungi
| Project/Area Number |
23658069
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied microbiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | 麹菌 / オートファジー / 糸状菌 |
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| Research Abstract |
Molecular biology of autophagy has started using yeast S. cerevisiae, and its important roles in eukaryotes have been revealed in not only yeast but also mammalian cells. However, little is known about filamentous fungi. Filamentous fungi such a Koji mold, Aspsergillus oryzae differentiates into conidia formation upon environmental change. Many autophagy-related genes from A. oryzae were isolated and characterized. Function and roles of autophagy specific to filamentous fungi have been analyzed.
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