2012 Fiscal Year Final Research Report
Development of DNA vaccine against intracellular microbial pathogens by using artificially synthesized genes
| Project/Area Number |
23658157
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
General fisheries
|
|---|
| Research Institution | Tokyo University of Marine Science and Technology |
|---|
Principal Investigator |
IKUO Hirono 東京海洋大学, 海洋科学技術研究科, 教授 (00270926)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Keywords | 人工遺伝子 / DNA ワクチン / 細胞内寄生性細菌 / コドン |
|---|
| Research Abstract |
We demonstrated that the DNA vaccine could induce higher expression of antigenic protein by codon optimization and establish high protection against intracellular pathogenic bacteria, Nocardia seriolae and Photobacterium damsela subsp. piscicida .
|
