2012 Fiscal Year Final Research Report
Advanced utilization of fermented food by-products: Development of Eco-immuno feeds"supporting health and environment
| Project/Area Number |
23658216
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Tohoku University |
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Principal Investigator |
KITAZAWA Haruki 東北大学, 大学院・農学研究科, 准教授 (10204885)
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| Co-Investigator(Kenkyū-buntansha) |
ASO Hisashi 東北大学, 大学院・農学研究科, 教授 (50241625)
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| Co-Investigator(Renkei-kenkyūsha) |
SUDA Yoshihito 宮城大学, 食産業学部, 准教授 (90404847)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 畜産物利用 / 発酵食品 / 未活用資源 / ブタ / イムノバイオティクス / イムノジェ ニクス / エコフィード |
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| Research Abstract |
In this study, for beneficial use of lactic acid bacterial fermentation liquid as underutilized resources, we focused on immunobiotics and immunogenics in the liquid and relating products, and examined fundamental analysis to develop as a novel “Immuno-Eco Feeds" contributing to the reduction of health hazards risk as livestock antimicrobial alternatives. Specifically, a safety of the liquid and immuneregulatory effects in porcine intestinal cells were evaluated, and in vivo confirmation study and in vitro detailed study of its mechanisms were also conducted.
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Research Products
(9 results)
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[Journal Article] Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichiacoli-mediated inflammation2013
Author(s)
Takanashi, N., Y. Tomosada, J. Villena, K. Murata, T. Takahashi, E. Chiba, M. Tohno, T. Shimazu, H. Aso, Y. Suda, S. Ikegami, H. Itoh, Y. Kawai, T. Saito, S. Alvarez, H. Kitazawa
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Journal Title
BMC Microbiol
Volume: 13(54)
Pages: 1-16
DOI
Peer Reviewed
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[Journal Article] Immunobiotic Lactobacillus jensenii modulates toll-like receptor4-induced inflammatory response via negative regulation in porcine antigen presenting cells2012
Author(s)
Villena, J., R. Suzuki, H. Fujie, E. Chiba, T. Takahashi, Y. Tomosada, T. Shimazu, H. Aso, S. Ohwada, Y. Suda, S. Ikegami, H. Itoh, S. Alvarez, T. Saito, H. Kitazawa
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Journal Title
Clin. Vac. Immunol
Volume: 19(7)
Pages: 1038-1053
DOI
Peer Reviewed
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