2013 Fiscal Year Final Research Report
Development of imaging system of follicles in mouse ovary using optical coherence tomography
| Project/Area Number |
23658220
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Yamagata University |
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Principal Investigator |
ABE Hiroyuki 山形大学, 理工学研究科, 教授 (10375199)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Yuki 山形大学, 大学院・理工学研究科, 准教授 (00333328)
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| Project Period (FY) |
2011 – 2012
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| Keywords | 光干渉断層画像化法 / 非侵襲計測 / 卵巣 / 生体機能評価 |
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| Research Abstract |
Optical coherence tomography (OCT) is analogous to ultrasound imaging except that it uses light instead of sound. OCT can provide a depth resolution of 1-20 um, which is one to two orders of magnitude higher than that of conventional ultrasound. OCT is a non-contact, non-invasive, fast imaging modality that provides real time, three-dimensional imaging capability. In this study, we examined, to the best of our knowledge, the first study that uses OCT for analysis of the developmental status of follicles in mouse ovary. The OCT image was identified each developmental stage from primary follicle (50 um in diameter) to antral follicle (350 um in diameter) in the ovary of 25.5-day-old mouse. Further we found time-varying OCT signals at the oocytes compared with around tissues.
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Research Products
(74 results)
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[Journal Article] Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by TGFbeta signaling down-regulation2011
Author(s)
Kurotani R., Okumura S., Matsubara T., Yokoyama U., Buckley J.R., Tomita T., Kezuka K., Nagano T., Esposito D., Taylor T.E., Gillette W.K., Ishikawa Y., Abe H., Ward J.M., Kimura S
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Journal Title
J. Biol. Chem
Volume: 286 (22)
Pages: 19682-19692
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[Presentation] 電気化学計測技術を応用したヒト胚品質評価法の開発と不妊治療における臨床的有用性に関する研究2013
Author(s)
熊迫陽子, 後藤香里, 小池恵, 大津英子, 長木美幸, 城戸京子, 佐藤晶子, 宇津宮隆史, 荒木康久, 阿部宏之
Organizer
第31回日本受精着床学会学術講演会 シンポジウム
Place of Presentation
大分県別府市, 別府国際コンベンションセンター
Year and Date
20130808-09
Invited
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[Presentation] 胚盤胞凍結保存液におけるヒドロキシプロピルセルロースの有用性2013
Author(s)
森智絵美, 高倉啓, 藪内晶子, 村田奈々, 阿部宏之, 勝股克成, 福田淳一郎, 青野文仁, 小林保, 加藤恵一
Organizer
第31回日本受精着床学会学術講演会
Place of Presentation
大分県別府市, 別府国際コンベンションセンター
Year and Date
20130808-09
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