2014 Fiscal Year Final Research Report
A surrogate virus for researches on foot-and-mouth disease
| Project/Area Number |
23658252
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied veterinary science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
|
| Keywords | ウイルス / レセプター / インテグリン |
|---|
| Outline of Final Research Achievements |
To examine whether wildlife may be responsible for spread of foot-and-mouth disease (FMD), I searched cell receptor molecules for FMD virus (FMDV) on the organs of Japanese wild deer. I identified integrin alpha V, beta 6, and beta 8, which are supposed to be the main receptor molecules for FMDV, suggesting that such deer are susceptible to FMDV, although I have not authenticated their functional roles using bovine rhinovirus 2 as a surrogate of FMDV.
|
| Free Research Field |
獣医ウイルス学
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