2012 Fiscal Year Final Research Report
Novel Oxidative Synthetic Transformations Driven by Chiral Oxoammmonium Salts
| Project/Area Number |
23659003
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Keywords | オキソアンモニウム塩 / アザアダマンタン / 不斉酸化 / アルコール酸化 / 不斉触 媒 / 分子認識 / ニトロキシルラジカル |
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| Research Abstract |
Novel synthetic use of azaadamantane-type oxoammonium salts has been exploited. It was found that 9-nor-azaadamantane N-oxy (Nor-AZADO) gives the corresponding oxoammonium salts that exhibit superior activities to AZADO derived oxoammonium salts. Several novel oxidative transformations using Nor-AZADO have been developed including (1) silyl enol ethers to a,b-unsaturated ketones and (2) silyl enol ethers to 1,2-diketones.
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Research Products
(6 results)
